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Updated: Dec 30, 2025
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Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog
Published on: November 5, 2014
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A novel label-free fluorescence assay for dipeptidyl peptidase 4 activity detection based on supramolecular
Yu Zhao1, Jiawen Zou, Yanyan Song
1Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, P. R. China. mysky@zju.edu.cn.
Chemical Communications (Cambridge, England)
|January 16, 2020
Abstract:
This article presents a new label-free fluorescence assay based on supramolecular self-assembly of cucurbit[7]uril and specific peptide Gly-Pro-Phe-Gly for monitoring DPP4 activity in clinical samples. It also displays a good potential application in high-throughput screening of DPP4 inhibitors.
