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Standard Precaution01:26

Standard Precaution

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Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
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Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

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Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
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Infection01:20

Infection

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
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Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
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Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

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Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
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Immunodeficiency Diseases01:25

Immunodeficiency Diseases

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Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
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Related Experiment Video

Updated: Dec 30, 2025

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo
07:56

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo

Published on: August 28, 2014

12.7K

[Defect coverage after severe soft tissue infections: when and how?]

N Möllhoff1, D Ehrl1, R E Giunta2

  • 1Abteilung für Hand‑, Plastische- und Ästhetische Chirurgie, Klinikum der Universität München, LMU München, Pettenkoferstr. 8a, 80336, München, Deutschland.

Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen
|January 16, 2020
PubMed
Summary
This summary is machine-generated.

Early coverage of severe soft tissue defects by plastic surgeons is crucial. Timely selection of reconstructive techniques, avoiding prolonged vacuum dressings, benefits patients and reduces healthcare burdens.

Keywords:
Free flap reconstructionNecrotizing fasciitisPlastic surgeryReconstructive surgerySkin transplantation

Related Experiment Videos

Last Updated: Dec 30, 2025

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo
07:56

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo

Published on: August 28, 2014

12.7K

Area of Science:

  • Plastic and Reconstructive Surgery
  • Wound Healing and Tissue Repair
  • Infectious Disease Management

Background:

  • Severe infections commonly result in significant soft tissue defects.
  • Prompt defect coverage is essential for patient recovery and outcomes.
  • Current treatment delays, such as prolonged vacuum dressings, negatively impact patients and healthcare resources.

Purpose of the Study:

  • To present essential reconstructive treatment approaches for large soft tissue defects.
  • To emphasize the importance of timely intervention by plastic surgeons.
  • To highlight the drawbacks of delayed defect coverage strategies.

Main Methods:

  • Review of reconstructive options including local flaps and microvascular free flaps.
  • Analysis of patient characteristics for optimal technique selection.
  • Case report-based presentation from a university hospital's plastic surgery practice.

Main Results:

  • Various reconstructive techniques are available for soft tissue defects.
  • Individualized patient assessment is key for selecting the best reconstructive method.
  • Early surgical intervention is superior to delayed methods like vacuum dressings.

Conclusions:

  • Timely plastic surgery intervention is vital for managing severe soft tissue defects.
  • Avoiding prolonged inpatient treatments with vacuum dressings is recommended.
  • Optimizing reconstructive techniques based on patient factors ensures better outcomes.