Sequence of late DNA replication in Cebus capucinus chromosomes and a standardized G-banded karyotype

We proposed a standardized G-banded idiogram (about 400 bands) for Cebus capucinus and established the complete late replication sequence for about 200 bands. Many chromosomes thought to be homologous on the basis of R-banding and gene mapping showed similar replication sequences to human and macaque chromosomes. Other supposed homologs had no good correspondence. Asynchrony was observed in some bands and a few of these are apparently evolutionarily conserved. A full understanding of the evolution of chromosome replication sequences can only be obtained when secure chromosomal homology has been established on a molecular DNA level; preferably with in situ suppression CISS hybridization of human chromosomal libraries. © 1992 Wiley-Liss, Inc.