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Updated: Dec 30, 2025

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Castleman's disease presenting with mechanical intestinal obstruction: A rare case
Abdulcabbar Kartal1, Eray Atlı2, Gürcan Vural3
1Department of General Surgery, Okan University Faculty of Medicine, İstanbul-Turkey.
Castleman's disease (CD), a rare lymphoproliferative disorder, can cause small bowel obstruction. This case highlights CD in the terminal ileum leading to mechanical intestinal obstruction requiring surgical intervention.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Castleman's disease (CD) is a rare lymphoproliferative disorder.
- Small bowel involvement by CD is exceptionally uncommon.
Observation:
- A 50-year-old male presented with symptoms of mechanical intestinal obstruction.
- Computed tomography revealed terminal ileum wall thickening and mesenteric lymphadenopathy.
- Surgical exploration identified a mass causing complete intestinal obstruction at the ileocecal valve.
Findings:
- The patient underwent ileocecal resection and ileocolonic anastomosis.
- Histopathological examination confirmed Castleman's disease as the cause of obstruction.
- This case demonstrates CD presenting as a small bowel mass.
Implications:
- Castleman's disease should be considered in the differential diagnosis of mechanical small bowel obstruction.
- Radiological findings of terminal ileum wall thickening and enlarged mesenteric lymph nodes may indicate CD.
- Early recognition and surgical management are crucial for patients with CD-induced intestinal obstruction.
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