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Protein Interaction Domains: Structural Features and Drug Discovery Applications (Part 2)

Marian Vincenzi1, Flavia Anna Mercurio1, Marilisa Leone1

  • 1Institute of Biostructures and Bioimaging, National Research Council (CNR), Via Mezzocannone 16, 80134 Naples, Italy.

Current Medicinal Chemistry
|January 17, 2020
PubMed
Summary

Protein Interaction Domains (PIDs) are key to cellular signaling and disease pathways. This review explores PIDs that bind standard peptides, highlighting their therapeutic potential and challenges in drug development.

Keywords:
Protein interaction domainsdrug discoveryinhibitorsligandspeptidesprotein-protein interactionssmall moleculesstructure

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