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Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

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New Insights into Bioactive Peptides: Design, Synthesis, Structure-Activity Relationship.

Flavia Anna Mercurio¹, Marilisa Leone¹

¹Institute of Biostructures and Bioimaging (IBB), National Research Council of Italy (CNR), Via Pietro Castellino 111, 80131 Naples, Italy.

International Journal of Molecular Sciences

|December 17, 2024

Summary

Peptides show promise as therapeutic compounds, attracting interest from academia and pharmaceutical companies for drug development. Further research is exploring their potential in treating various diseases.

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Area of Science:

Biochemistry and Medicinal Chemistry
Drug Discovery and Development

Background:

Peptides are increasingly recognized for their therapeutic potential.
Both academic research and pharmaceutical industries are investing in peptide-based drug discovery.

Discussion:

Peptides offer unique advantages as therapeutic agents.
Their development presents opportunities for novel treatment strategies.

Key Insights:

Significant academic and pharmaceutical interest in peptides as drug candidates.
Peptides represent a growing area for therapeutic innovation.

Outlook:

Continued exploration of peptide therapeutics is expected.
Advancements in peptide synthesis and engineering will drive future applications.