Wound Healing Process After Thermomechanical Skin Ablation

Area of Science:

• Dermatology
• Aesthetic Medicine
• Regenerative Medicine

Background:

• Energy-based devices are common for skin ablation.
• A new thermomechanical ablation technique (Tixel©) has been developed.
• This study investigates wound healing and clinical outcomes of Tixel© skin ablation.

Observation:

• Six female participants received Tixel© treatment on forearm skin.
• Microscopy and clinical evaluations were performed on days 1, 2, 7, and 14 post-treatment.
• Parameters used: 600 µm protrusion, 12 ms pulse duration.

Findings:

• Erythema and mild edema resolved within 14 days.
• No post-inflammatory hyperpigmentation or scarring occurred.
• Homogeneous micro-ablation zones showed complete epidermal restoration with a honeycomb pattern by day 14.

Implications:

• Thermomechanical skin ablation demonstrates accelerated wound healing compared to other fractionated methods.
• The findings support Tixel© as an effective skin ablation technique.
• Potential for recommended treatment intervals of 2-4 weeks for Tixel© procedures.