Related Experiment Video
Updated: Dec 30, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Internalized and Anticipated Stigmatization in Patients With Gout
Maria Kleinstäuber1, Leonie Wolf2, Annie S K Jones3
1University of Otago, Dunedin, New Zealand, and Philipps-University, Marburg, Germany.
Stigma impacts patients with gout, particularly younger individuals experiencing negative emotions and considering nonadherence to urate-lowering medication. This highlights a need for targeted support for gout patients facing illness-related stigma.
Area of Science:
- Rheumatology
- Psychosocial Medicine
- Health Disparities
Background:
- Gout is a chronic condition requiring long-term management.
- Illness-related stigma can negatively affect patient outcomes and treatment adherence.
- Understanding factors associated with stigma perception in gout is crucial for effective patient care.
Purpose of the Study:
- To examine the associations between stigma perception (internalized and anticipated) and demographic, clinical, and psychosocial factors in patients with gout.
- To identify predictors of stigma experience in this patient population.
Main Methods:
- A cross-sectional study involving 50 patients with gout on urate-lowering medication.
- Data collected via questionnaires assessing internalized/anticipated stigma, demographics, gout severity, and psychosocial variables (illness perceptions, disability, body satisfaction, nonadherence).
- Serum urate levels were recorded from recent blood tests.
Main Results:
- 26% of patients reported internalized stigma, and 26% anticipated stigma from family/friends; 14% anticipated stigma from healthcare workers.
- Univariate analyses linked younger age, non-New Zealand European ethnicity, gout pain severity, negative illness perceptions, higher disability, and intentional nonadherence to increased stigma.
- Multivariate analysis identified younger age, emotional illness response, and intentional nonadherence as significant predictors of anticipated stigma.
Conclusions:
- A notable subgroup of gout patients experiences internalized and anticipated illness-related stigma.
- Stigma in gout is associated with younger age, negative emotional responses to illness, and intentions toward nonadherence with treatment.
- These findings suggest a need for interventions addressing stigma and its psychosocial correlates in gout management.
Related Concept Videos
Generalized Anxiety Disorder
Nursing Assessment of the Genitourinary System I: Health History
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Gastritis-I: Introduction and Types
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Acute Pancreatitis II: Clinical Manifestations and Management

