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Updated: Dec 30, 2025
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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
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Endophthalmitis in HIV Infection
Theodora Tsirouki1, Jonel Steffen2, Anna Dastiridou1
1Department of Ophthalmology, University of Thessaly , Larissa, Greece.
Ocular Immunology and Inflammation
|January 17, 2020
Summary
Endophthalmitis is a rare but serious eye condition in people with Human Immunodeficiency Virus (HIV). Early combination antiretroviral therapy (cART) is crucial for preventing endophthalmitis in HIV patients.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Immunology
Background:
- The role of Human Immunodeficiency Virus (HIV) infection in exogenous and endogenous endophthalmitis remains unclear.
- Endophthalmitis is a sight-threatening condition that can affect individuals with HIV.
Purpose of the Study:
- To assess the potential role of HIV as a risk factor for endophthalmitis.
- To evaluate HIV as a poor prognostic feature in endophthalmitis cases.
Main Methods:
- A comprehensive literature review was conducted.
- Evidence was gathered from retrospective case series and case reports.
Main Results:
- Literature on endophthalmitis in HIV patients is scarce due to the condition's rarity and the diversity of endophthalmitis types.
- Endophthalmitis in HIV patients is infrequent but can be devastating.
Conclusions:
- Endophthalmitis often occurs in severely immunosuppressed HIV patients with low CD4 counts.
- Early introduction of combination antiretroviral therapy (cART) is vital for immune reconstitution and endophthalmitis prevention in the HIV population.
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