Related Experiment Video

Updated: Dec 30, 2025

Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.2K

A finite element model for insulin adsorption in ICU infusion sets

Jennifer L Knopp, Kaia Bishop, J Geoffrey Chase

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |January 18, 2020
    PubMed

    More Related Videos

    A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device07:55

    A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device

    Published on: January 26, 2010

    12.3K
    Insulin Injection and Hemolymph Extraction to Measure Insulin Sensitivity in Adult Drosophila melanogaster05:52

    Insulin Injection and Hemolymph Extraction to Measure Insulin Sensitivity in Adult Drosophila melanogaster

    Published on: June 30, 2011

    20.3K

    Related Concept Videos

    One-Compartment Model: IV Infusion01:09

    One-Compartment Model: IV Infusion

    Intravenous (IV) infusion is often utilized when continuous and controlled drug delivery is necessary, such as during surgery or in the treatment of chronic diseases. This method offers numerous advantages, including immediate drug action, precise control over dosage, and bypassing the first-pass metabolism.
    The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
    442
    Two-Compartment Open Model: IV Infusion01:15

    Two-Compartment Open Model: IV Infusion

    A two-compartment model is a vital tool in pharmacokinetics, providing an essential understanding of drug behavior, especially for those administered via zero-order intravenous infusion. This model outlines two compartments: the central compartment, where elimination occurs, and the peripheral compartment.
    The model illustrates the decrease in plasma drug concentration from the central compartment with a specific equation. It shows that under steady-state conditions, the drug's input rate...
    509
    One-Compartment Open Model for IV Bolus Administration: General Considerations01:19

    One-Compartment Open Model for IV Bolus Administration: General Considerations

    The one-compartment model is a pharmacokinetic tool that models the body as a single, uniform compartment, facilitating the understanding of drug distribution and elimination. This model is particularly beneficial for intravenous (IV) bolus administration, where the drug rapidly circulates throughout the body.
    The drug's presence in the body is defined by an equation representing the difference between the rates of drug entry and exit. Key parameters—elimination rate constant,...
    617
    Insulin Formulations: Types and Delivery01:27

    Insulin Formulations: Types and Delivery

    Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
    Short-acting insulins are divided into...
    569
    Compartment Models: Single-Compartment Model01:14

    Compartment Models: Single-Compartment Model

    The single-compartment model serves as a simplified representation of the human body. This model assumes that the body functions as a single, well-mixed open compartment. When a drug is administered intravenously, it enters the body and quickly distributes uniformly. The drug then undergoes biotransformation and elimination, ultimately leaving the body. The volume of this compartment is referred to as the apparent volume of distribution into which the drug can uniformly distribute. In this...
    2.9K
    Two-Compartment Open Model: IV Bolus Administration01:18

    Two-Compartment Open Model: IV Bolus Administration

    The two-compartment model for intravenous (IV) bolus administration illustrates drug distribution in the body, subdividing it into central and peripheral compartments. This model operates on the concept of two-compartment kinetics. The drug's plasma concentration shows a bi-exponential decline following IV bolus administration, signaling the presence of two disposition processes: distribution and elimination.
    The disparity between drug input and the sum of drug transfer rates between...
    1.0K