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Cortical Stimulation Induces Network-Wide Coherence Change In Non-Human Primate Somatosensory Cortex.

Julien A Bloch, Karam Khateeb, Daniel B Silversmith

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |January 18, 2020
    PubMed

    Abstract:

    Stimulation of the cortex can modulate the connectivity between brain regions. Although targeted neuroplasticity has been demonstrated in-vitro, in-vivo models have been inconsistent in their response to stimulation. In this paper, we tested various stimulation protocols to characterize the effect of stimulation on coherence in the non-human primate cortex in-vivo. We found that the stimulation latency, the state of the cortex during stimulation, and the stimulation site all affected the modulation of cortical coherence. We further investigated features of a resting-state network that could predict how a connection is likely to change with stimulation.

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