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Related Experiment Video

Updated: Dec 30, 2025

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform
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Persistent postural-perceptual dizziness: Clinical and neurophysiological study.

Ivan Adamec1, Snježana Juren Meaški1, Magdalena Krbot Skorić2

  • 1University Hospital Center Zagreb, Department of Neurology, Zagreb, Croatia.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|January 18, 2020
PubMed
Summary

Persistent postural-perceptual dizziness (PPPD) affects 19% of patients in a tertiary vertigo clinic, often triggered by vestibular neuritis. Comprehensive neurophysiological testing is valuable for assessing vestibular function in PPPD patients.

Keywords:
NeurophysiologyPersistent postural-perceptual dizzinessVertigo

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Area of Science:

  • Neurology
  • Otolaryngology
  • Vestibular Science

Background:

  • Persistent postural-perceptual dizziness (PPPD) is a common cause of chronic dizziness.
  • Understanding its clinical and neurophysiological profile is crucial for diagnosis and management.

Purpose of the Study:

  • To evaluate the clinical and neurophysiological characteristics of patients diagnosed with PPPD.
  • To assess the utility of comprehensive vestibular function testing in PPPD.

Main Methods:

  • Cross-sectional study of 147 consecutive dizziness patients in a tertiary vertigo clinic.
  • Data extraction included demographics, symptom duration, triggers, and results from caloric testing, video head impulse test (vHIT), and vestibular evoked myogenic potentials (oVEMP and cVEMP).

Main Results:

  • 28 patients (19%) were diagnosed with PPPD (68% female, mean age 59.5 years).
  • Median symptom duration was 23 months; common triggers included vestibular neuritis (39.3%) and BPPV (10.7%).
  • Abnormalities were found in caloric testing (n=6), vHIT (n=13), and VEMP (n=17), with many showing multiple canal or combined VEMP pathologies.

Conclusions:

  • PPPD represents a significant proportion of patients in specialized vertigo clinics.
  • Clinical and neurophysiological findings highlight the presence of vestibular dysfunction in PPPD.
  • Complete neurophysiological assessment is beneficial for evaluating vestibular function in PPPD patients.