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Updated: Dec 30, 2025

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Weight variability during self-monitored weight loss predicts future weight loss outcome
Leora Benson1, Fengqing Zhang2, Hallie Espel-Huynh2
1Department of Psychology, Drexel University, Philadelphia, PA, USA. lb863@drexel.edu.
Greater weight variability during early weight loss predicts poorer long-term weight management outcomes. This finding highlights weight variability as a key predictor for future weight change success.
Area of Science:
- Obesity research
- Behavioral science
- Data science
Background:
- Obesity treatments often lack long-term efficacy.
- Understanding predictors of weight change is crucial for effective obesity management.
Purpose of the Study:
- To test if weight variability during early weight loss predicts long-term weight management success.
- To investigate weight variability as an independent predictor of weight change.
Main Methods:
- Utilized data from 24,009 American users of Withings smart scales with over a year of weight data.
- Calculated weight variability using multilevel modeling of weekly average weights from the first 12 weeks of weight loss.
- Employed linear regressions to assess the predictive power of weight variability on weight change at 48, 72, and 96 weeks.
Main Results:
- Higher weight variability in the initial 12 weeks predicted less weight loss and more weight regain at 48, 72, and 96 weeks.
- These predictions held true even after controlling for baseline BMI and initial weight change.
- An interaction effect indicated that weight variability's impact on later weight change was more pronounced in individuals with lower baseline BMI.
Conclusions:
- Early weight variability is a significant predictor of long-term weight loss outcomes in a large population.
- Weight variability should be considered a critical factor in predicting future weight change.
- Further research is necessary to elucidate the underlying mechanisms driving this association.
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