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Quantitative Susceptibility Mapping: Technical Considerations and Clinical Applications in Neuroimaging
Selvadasan Vinayagamani1, R Sheelakumari1, Sekar Sabarish1
1Department of Imaging Sciences and Interventional Radiology, Trivandrum, India.
Journal of Magnetic Resonance Imaging : JMRI
|January 18, 2020
Summary
Quantitative susceptibility mapping (QSM) is a novel MRI technique. This review explores QSM
Area of Science:
- Neuroimaging
- Biomarkers
- Medical Physics
Background:
- Quantitative susceptibility mapping (QSM) is an advanced magnetic resonance imaging (MRI) technique.
- QSM quantifies magnetic susceptibility, revealing key brain components like iron and calcium.
Purpose of the Study:
- To review the fundamental principles of QSM.
- To summarize the diverse clinical applications of QSM in neuroimaging.
Main Methods:
- Review of existing literature on QSM physics and applications.
- Synthesis of QSM's role in studying brain metabolism and disease.
Main Results:
- QSM accurately maps magnetic susceptibility sources in the brain.
- QSM enables the measurement of cerebral metabolic rate of oxygen, a potential disease biomarker.
Conclusions:
- QSM holds significant promise as an imaging biomarker for neurological diseases.
- The technique offers wide-reaching clinical applications in understanding brain oxygen supply disruptions.
