Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Photoluminescence: Applications

Photoluminescence: Applications

Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...

The Photochemical Reaction Center

The Photochemical Reaction Center

Reaction centers are pigment-protein complexes that initiate energy conversion from photons to chemical entities. Therefore, photochemical reaction center is a more appropriate term that describes these complexes. The Nobel laureates Robert Emerson and William Arnold provided the first experimental evidence of photochemical reaction centers by demonstrating the participation of nearly 2,500 chlorophyll molecules for the release of just one molecule of oxygen. Despite thousands of photosynthetic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

AI-Powered Lesion-Level Tumor Growth Inhibition Modeling Improves Model Stability and Prognostic Association With PFS.

CPT: pharmacometrics & systems pharmacology·2026

Same author

Fluorescent self-reporting theranostic platforms for tumour therapy: from cytotoxin release monitoring to therapeutic feedback evaluation.

Journal of materials chemistry. B·2026

Same author

Explainable MRI radiomics of the basal ganglia and ventral midbrain distinguishes Parkinson's disease, SWEDD, and healthy controls.

NeuroImage·2026

Same author

Smartphone Video Hand Gesture Analysis for Psoriatic Arthritis Assessment.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

Same author

Smartphone Typing Dynamics for Assessing Hand Function in Psoriatic Arthritis: A Proof-of-Concept Study.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

Same author

Real-Time Tracking of ASCT2-Mediated Glutamine Uptake in Living Tumors With a Bioorthogonal Bioluminescent Probe.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025

Same journal

Crosslinker-free PVA hydrogel incorporating a water-soluble Ir(III) photosensitizer for antibacterial photodynamic applications in wound healing.

Journal of materials chemistry. B·2026

Same journal

Precise microfluidic engineering of mRNA lipid nanoparticle-loaded polycaprolactone microcapsules for sustained delivery.

Journal of materials chemistry. B·2026

Same journal

Multifunctional polysulfone/strontium silicate composites with tunable properties through silane functionalization.

Journal of materials chemistry. B·2026

Same journal

Melanocortin 1 receptor-targeted peptide-functionalized liposomes for enhanced melanocyte-preferential drug delivery and anti-melanogenic efficacy.

Journal of materials chemistry. B·2026

Same journal

Recent progress in side-chain amino acid-based polymers: synthesis, self-assembly, and emerging biomedical applications.

Journal of materials chemistry. B·2026

Same journal

Bioinspired electrospun nanofibrous dressings loaded with Mentha-derived exosome-like vesicles for antibacterial and immunomodulatory burn healing.

Journal of materials chemistry. B·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 30, 2025

Detecting, Visualizing and Quantitating the Generation of Reactive Oxygen Species in an Amoeba Model System

Detecting, Visualizing and Quantitating the Generation of Reactive Oxygen Species in an Amoeba Model System

Published on: November 5, 2013

Aggregation-induced emission luminogens for RONS sensing.

Jun Dai¹, Chong Duan, Yu Huang

¹Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. shixuanwang@tjh.tjmu.edu.cn.

Journal of Materials Chemistry. B

|January 18, 2020

Summary

This summary is machine-generated.

This review highlights aggregation-induced emission (AIE) luminogens (AIEgens) as advanced fluorescent bioprobes for detecting reactive oxygen and nitrogen species (RONS). These AIEgens offer superior sensing capabilities for oxidative stress in disease diagnostics and therapy.

More Related Videos

Author Spotlight: High-Throughput Measurement of Intracellular ROS Levels in Hepatocellular Lines

Author Spotlight: High-Throughput Measurement of Intracellular ROS Levels in Hepatocellular Lines

Published on: January 19, 2024

Real-Time Detection of Reactive Oxygen Species Production in Immune Response in Rice with a Chemiluminescence Assay

Real-Time Detection of Reactive Oxygen Species Production in Immune Response in Rice with a Chemiluminescence Assay

Published on: November 25, 2022

Related Experiment Videos

Last Updated: Dec 30, 2025

Detecting, Visualizing and Quantitating the Generation of Reactive Oxygen Species in an Amoeba Model System

Detecting, Visualizing and Quantitating the Generation of Reactive Oxygen Species in an Amoeba Model System

Published on: November 5, 2013

Author Spotlight: High-Throughput Measurement of Intracellular ROS Levels in Hepatocellular Lines

Author Spotlight: High-Throughput Measurement of Intracellular ROS Levels in Hepatocellular Lines

Published on: January 19, 2024

Real-Time Detection of Reactive Oxygen Species Production in Immune Response in Rice with a Chemiluminescence Assay

Real-Time Detection of Reactive Oxygen Species Production in Immune Response in Rice with a Chemiluminescence Assay

Published on: November 25, 2022

Area of Science:

Biomedical Engineering
Chemical Sensing
Molecular Imaging

Background:

Reactive oxygen and nitrogen species (RONS) are critical mediators of oxidative stress implicated in numerous diseases.
Accurate in situ monitoring of biologically relevant RONS is essential for understanding disease mechanisms and developing treatments.
Fluorescent bioprobes offer sensitive and rapid detection methods for biomedical applications.

Purpose of the Study:

To review the application of aggregation-induced emission (AIE) luminogens (AIEgens) as fluorescent bioprobes for sensing reactive oxygen and nitrogen species (RONS).
To discuss the sensing principles and advantages of AIEgens in RONS detection.
To provide a perspective on the future development of AIEgen-based RONS sensing for diagnostics and therapy.

Main Methods:

Review of current literature on AIEgens for RONS sensing.
Introduction to the concept of RONS and AIE bioprobe sensing principles.
Summarization of representative examples of AIEgens used in RONS detection.

Main Results:

AIEgens possess unique photophysical properties, including large Stokes' shifts, high signal-to-noise ratios, and excellent photostability, making them superior for RONS sensing.
AIE bioprobes have demonstrated significant potential in various biomedical applications for detecting oxidative stress markers.
The review consolidates current advancements and showcases successful applications of AIEgens in RONS sensing.

Conclusions:

AIEgens represent a powerful class of fluorescent bioprobes for the accurate and reliable in situ monitoring of RONS.
The unique advantages of AIEgens facilitate their application in diagnostic analysis and therapeutic interventions related to oxidative stress.
Further research and development in AIEgen-based RONS sensing are expected to drive innovation in disease diagnosis and treatment.