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Casein-based hydrogels: A mini-review.
Luis Gustavo Lima Nascimento1, Federico Casanova2, Naaman Francisco Nogueira Silva3
1Departamento de Tecnologia de Alimentos, Universidade Federal de Viçosa (UFV), 36570-900 Viçosa, Minas Gerais, Brazil.
Food Chemistry
|January 18, 2020
Summary
Casein-based hydrogels offer a versatile, eco-friendly platform for drug delivery. Their unique properties enable efficient encapsulation and controlled release of various molecules for biomedical applications.
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Drug Delivery Systems
Background:
- Casein-based hydrogels are gaining attention due to their biocompatibility, biodegradability, and low cost.
- These hydrogels can exist in various forms, including particle and macro hydrogels.
- They possess the ability to form networks and encapsulate, protect, and release biomolecules.
Purpose of the Study:
- To review recent advancements in casein-based hydrogel research.
- To explore the application of casein-based hydrogels in drug delivery for both hydrophobic and hydrophilic molecules.
- To discuss the food and biomedical potential and future prospects of these hydrogels.
Main Methods:
- Literature review of recent research on casein-based hydrogels.
- Analysis of studies focusing on drug encapsulation and release mechanisms.
- Evaluation of the physicochemical properties and applications of casein-based hydrogels.
Main Results:
- Casein-based hydrogels demonstrate tunable network structures and controlled release capabilities.
- They are effective in delivering both hydrophobic and hydrophilic drugs.
- Recent research highlights their potential in various food and biomedical applications.
Conclusions:
- Casein-based hydrogels represent a promising biomaterial for advanced drug delivery systems.
- Their versatility and favorable properties support their use in both food and biomedical fields.
- Further research can unlock novel applications and optimize their performance for therapeutic purposes.

