A feasible sonochemical approach to synthesize CuO@CeO₂ nanomaterial and their enhanced non-enzymatic sensor...

A nanostructured and high conductive cupric oxide (CuO NPs) with hierarchical CeO₂ sheets-like structure was synthesized by a facile sonochemical approach. Furthermore, CuO/CeO₂ nanostructure is synthesized by high-intensity ultrasonic probe (Ti-horn, 50 kHz and 100 W) at ambient air. Moreover, the synthesized CuO/CeO₂ material was characterized by various analytical techniques including FESEM, EDX, XRD and electrochemical methods. Then, the synthesized CuO/CeO₂ composite was applied for the electrocatalytic detection of dopamine using CV and DPV techniques. In addition, the CuO/CeO₂ modified electrode has good electrocatalytic performance with high linear range from 0.025 to 98.5 µM towards the determination of dopamine drug and high sensitivity of the CuO/CeO₂ modified drug sensor was calculated as 16.34 nM and 4.823 μA·µM^-1·cm^-2, respectively. Moreover, a repeatability, reproducibility and stability of the CuO@CeO₂ mixture modified electrode were analyzed towards the determination of dopamine biomolecule. Interestingly, the real time application of CuO@CeO₂ modified electrode was established in different serum and drug samples.