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Corynebacterium striatum: an emerging respiratory pathogen.
Malini Shariff1, Aditi Aditi2, Kiran Beri3
1Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India. malini.shariff@gmail.com.
Journal of Infection in Developing Countries
|January 19, 2020
Summary
Corynebacterium striatum, a multi-drug resistant pathogen, can cause respiratory infections like COPD exacerbations and pneumonia. Further identification is crucial as these bacteria are often resistant to multiple antibiotics.
Area of Science:
- Clinical Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Background:
- Corynebacterium spp. are often overlooked as normal flora.
- Corynebacterium striatum is an emerging multi-drug resistant pathogen.
- This organism infrequently causes respiratory tract infections.
Purpose of the Study:
- To investigate the clinical and microbiological characteristics of respiratory infections caused by Corynebacterium striatum.
- To assess the antimicrobial susceptibility and molecular typing of C. striatum isolates.
Main Methods:
- Retrospective review of clinical data from hospitalized patients.
- Antimicrobial susceptibility testing of C. striatum isolates.
- Random Amplification of Polymorphic DNA (RAPD) typing for outbreak investigation.
Main Results:
- 15 C. striatum isolates from 11 patients were analyzed.
- Infections primarily involved exacerbation of chronic obstructive pulmonary disease (COPD) and pneumonia.
- All isolates exhibited multi-drug resistance.
- RAPD typing indicated no patient-to-patient transmission.
Conclusions:
- Corynebacterium spp. should be recognized as potential pathogens.
- Species-level identification of suspicious isolates is essential.
- Corynebacterium striatum frequently displays multi-drug resistance, necessitating careful clinical consideration.
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