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Thyroid function in psychosis following childbirth.

D E Stewart1, A M Addison, G E Robinson

  • 1Department of Psychiatry, University of Toronto, Ont., Canada.

The American Journal of Psychiatry
|December 1, 1988
PubMed
Summary
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Postpartum thyroiditis is not a significant cause of postpartum psychosis. Studies found no thyroid differences between women with postpartum psychosis and healthy controls.

Area of Science:

  • Psychiatry
  • Endocrinology
  • Obstetrics

Background:

  • Postpartum psychosis is a severe mental health condition occurring after childbirth.
  • Postpartum thyroiditis, an autoimmune thyroid condition, has been hypothesized as a potential cause.

Purpose of the Study:

  • To investigate the association between postpartum thyroiditis and postpartum psychosis.
  • To determine if thyroid dysfunction or antibodies are more prevalent in women with postpartum psychosis.

Main Methods:

  • Compared thyroid function tests and thyroid antibody levels in 30 hospitalized women with postpartum psychosis.
  • Matched 30 control subjects for age and time since delivery.

Main Results:

  • No significant differences in thyroid function were observed between the psychotic and control groups.

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  • The prevalence of thyroid antibodies did not significantly differ between the two groups.

    • Conclusions:

    • Postpartum thyroiditis is unlikely to be a primary cause of postpartum psychosis.
    • Further research may explore other etiological factors for postpartum psychosis.