Pyoderma gangrenosum-like lesions provocated by botulinum injections

Area of Science:

• Dermatology
• Toxicology
• Cosmetic Procedures

Background:

• Botulinum toxin (BoNT) is widely used for medical and cosmetic purposes.
• The increasing popularity of cosmetic procedures has led to a rise in unregistered BoNT products.
• Unregistered products pose a risk of adverse reactions due to unknown composition and manufacturing standards.

Observation:

• A 51-year-old woman received an unregistered BoNT injection from a beautician.
• She developed lesions at the injection sites resembling pyoderma gangrenosum.
• The clinical presentation, histopathology, and treatment response confirmed the diagnosis.

Findings:

• This case represents the first reported instance of pyoderma gangrenosum-like reaction following BoNT administration.
• The reaction was attributed to the use of an unregistered botulinum toxin product.
• Histopathological examination supported the diagnosis of pyoderma gangrenosum.

Implications:

• Highlights the potential dangers associated with using non-medical grade or unregistered botulinum toxin products.
• Underscores the importance of seeking treatments from qualified medical professionals.
• Emphasizes the need for regulatory oversight of cosmetic products to prevent patient harm.