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Updated: Dec 30, 2025
Bergmeyer Glucose Quantification for Microbiological Samples
Published on: January 17, 2025
Amperometric Detection of dsDNA using an Acridine-Orange-Modified Glucose Oxidase
Daliborka Jambrec1, Klaus Lammers1, Tim Bobrowski1
1Analytical Chemistry-Center for Electrochemical Sciences (CES), Ruhr-Universität Bochum, Universitätsstrasse 150, 44780, Bochum, Germany.
Abstract:
Invited for this month's cover is the group of Prof. Dr. Wolfgang Schuhmann, Dr. Daliborka Jambrec and Dr. Adrian Ruff at Ruhr-Universität in Bochum, Germany. The cover picture shows a novel procedure for the preferential post-hybridization labeling of double-stranded DNA based on the intercalating compound acridine orange, which was covalently bound to glucose oxidase. Labeling with a highly active biocatalyst allows for a simple and sequence-independent amplification of the signal proportional to the amount of hybridized DNA that may be coupled with other amplification strategies. Read the full text of the article at 10.1002/cplu.201700279.
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