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Updated: Dec 30, 2025

Author Spotlight: Tracking Electrochemistry on Single Nanoparticles with Surface-Enhanced Raman Scattering Spectroscopy and Microscopy
Published on: May 12, 2023
Local Surface Modifications Investigated by Combining Scanning Electrochemical Microscopy and Surface-Enhanced Raman
Jan Clausmeyer1, Michaela Nebel2, Stefanie Grützke1
1Analytical Chemistry, Center for Electrochemical Sciences (CES), Ruhr-Universität Bochum, Universitätsstrasse 150, 44780, Bochum, Germany.
Abstract:
Scanning electrochemical microscopy (SECM) is coupled with surface-enhanced Raman scattering (SERS) microscopy to characterize local surface modifications. SECM is utilized for the surface patterning of para-nitrothiophenol self-assembled monolayers (SAMs) in the direct mode of SECM with a subsequent readout of the chemical patterns by means of combined SECM-SERS. The SECM-SERS combination allows monitoring of local electrochemical processes and provides simultaneous complementary spectroscopic information. The reaction products upon SAM reduction, specifically p-aminothiophenol groups, are distinguished from the pristine SAM and locally ruptured areas.
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