Related Experiment Video
Updated: Dec 30, 2025

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Intravascular lithotripsy to treat an underexpanded coronary stent: 4-Month angiographic and OCT follow-up
Mohammed Alawami1, Sharmaine Thirunavukarasu1, Javed Ahmed2
1Manchester Royal Infirmary, Manchester, UK.
Insights
Intravascular lithotripsy effectively treated underexpanded stents after percutaneous coronary intervention for severe calcified coronary artery disease. This approach ensured excellent stent expansion and long-term lumen gain, improving patient outcomes.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
Background:
- Percutaneous coronary intervention (PCI) is a standard treatment for coronary artery disease.
- Severe calcification and underexpanded stents pose significant challenges during PCI, potentially leading to suboptimal outcomes.
Observation:
- A 79-year-old man with stable angina presented with a severely calcified left circumflex lesion requiring PCI.
- Despite aggressive lesion preparation with balloon angioplasty and rotablation, the implanted stent remained underexpanded and unresponsive to post-dilatation.
Findings:
- The patient underwent intravascular lithotripsy (IVL) six weeks later, achieving excellent stent expansion.
- Follow-up angiography and optical coherence tomography (OCT) at four months demonstrated sustained acute lumen gain without stent recoil or in-stent restenosis.
Implications:
- Intravascular lithotripsy is a viable and effective treatment option for managing underexpanded stents in complex calcified lesions.
- This case highlights the potential of IVL to improve PCI success rates and long-term stent patency in challenging coronary anatomies.
Abstract:
We report the case of a 79-year-old man with stable angina who underwent percutaneous coronary intervention to a severe and calcified left circumflex lesion. Despite extensive preparation of the lesion with high-pressure balloon predilatation and rotablation, the implanted stent was grossly underexpanded and failed to respond to high-pressure balloon postdilatation. The patient was readmitted 6 weeks later for intravascular lithotripsy that resulted in excellent stent expansion. Coronary angiography with optical coherence tomography 4 months later revealed sustained acute lumen gain with no evidence of stent recoil or in-stent restenosis.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Urinary Tract Calculi VI: Surgical Management
Angina IV: Management
