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Updated: Dec 30, 2025
Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
A single-center experience in the management of head and neck lymphangiomas
Paolo Aluffi Valletti1, Matteo Brucoli2, Paolo Boffano3
1ENT Division, University Hospital "Maggiore della Carità", University of Eastern Piedmont, Novara, Italy.
Introduction:
Lymphangiomas are relatively uncommon head and neck region lymphatic malformations. Although surgery can be still considered the mainstay of treatment, sclerotherapy by OK-432 is becoming a widespread treatment option. The aim of this article is to present and discuss the management and outcomes of a series of cases of lymphangiomas.
Methods:
All patients with lymphangiomas who were treated from 2010 to 2018 were reviewed. The following data were recorded: age, gender, subtype, staging, type of treatment, outcome, and recurrence.
Results:
Fifteen patients (9 females, 6 males) were included with 2 microcystic and 13 macrocystic lymphangiomas. Six patients underwent surgery with excision (5 with a complete success, one with a fair success), whereas the remaining 9 subjects underwent sclerotherapy by OK-432 (6 with a complete success, 3 with a fair success). No postoperative complications were observed.
Conclusions:
All modes of treatment are important in properly selected patients affected by lymphangiomas. OK-432 therapy is a safe and effective option in the treatment of head and neck lymphangiomas.
