Diffuse cystic lung adenocarcinoma: a case report and literature review

Lung adenocarcinoma can exhibit a variety of radiological manifestations. However, the presence of diffuse cystic lesions in both lungs is extremely rare. Here, we report a case of a middle-aged woman with a primary lung adenocarcinoma that manifested as diffuse cystic lesions in bilateral lungs. Histopathological examination ultimately confirmed the lung adenocarcinoma. The patient was treated with the epidermal growth factor receptor (EGFR) inhibitor Gefitinib and remained stable during 18 months of follow-up. Knowledge of uncommon radiological performances of lung adenocarcinoma characterized by diffuse cystic imaging is important in suggesting the diagnosis and preventing misinterpretation.