Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

361
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
361
Autoimmune Disorders01:29

Autoimmune Disorders

1.4K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
1.4K
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

379
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
379
Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

233
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
233
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF01:24

Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF

396
Tumor Necrosis Factor (TNF), a proinflammatory cytokine, contributes significantly to the inflammation seen in Crohn's disease. It exists as soluble TNF and membrane-bound TNF, with actions mediated through TNF receptors (TNFR). TNFR activation leads to the release of proinflammatory cytokines, T-cell activation, collagen production, and leukocyte migration, all contributing to inflammation in Crohn's disease. Anti-TNF monoclonal antibodies, namely infliximab (Remicade), adalimumab...
396
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

244
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
244

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Consecutive PRES and diffuse alveolar hemorrhage in a patient with active lupus nephritis and antiphospholipid antibodies: a case report and systematic literature review.

BMC nephrology·2026
Same author

Socioeconomic status in Behçet's syndrome.

Clinical and experimental rheumatology·2026
Same author

Efficacy and safety of JAK inhibitors in Behçet syndrome: systematic literature review.

Seminars in arthritis and rheumatism·2026
Same author

Treat-to-target in Behçet syndrome.

Nature reviews. Rheumatology·2026
Same author

Potential Confounding by Weight Loss: Comment on the article by Jorge et al.

Arthritis & rheumatology (Hoboken, N.J.)·2026
Same author

ANCA-associated vasculitis presenting with tongue necrosis and severe gastrointestinal involvement.

Clinical and experimental rheumatology·2026

Related Experiment Video

Updated: Dec 30, 2025

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
10:21

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma

Published on: September 20, 2024

688

Takayasu's arteritis: associated inflammatory diseases.

Sinem Nihal Esatoglu1, Ayse Merve Ok2, Didar Ucar3

  • 1Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Clinical and Experimental Rheumatology
|January 24, 2020
PubMed
Summary

Takayasu's arteritis (TAK) frequently co-occurs with other inflammatory conditions like inflammatory bowel disease (IBD) and ankylosing spondylitis (AS). This study found approximately one-fifth of TAK patients had these associated inflammatory disorders.

More Related Videos

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

7.5K
An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

906

Related Experiment Videos

Last Updated: Dec 30, 2025

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
10:21

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma

Published on: September 20, 2024

688
An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

7.5K
An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

906

Area of Science:

  • Rheumatology
  • Internal Medicine
  • Immunology

Background:

  • Takayasu's arteritis (TAK) is a rare, chronic inflammatory disease affecting large arteries.
  • Previous case reports suggest a potential co-occurrence of TAK with other inflammatory and autoimmune disorders.
  • A formal study is needed to quantify the frequency of these co-existing conditions in a large TAK cohort.

Purpose of the Study:

  • To determine the frequency of co-existing inflammatory disorders in patients with Takayasu's arteritis.
  • To investigate the prevalence of specific conditions such as inflammatory bowel disease (IBD), ankylosing spondylitis (AS), and Behçet's syndrome (BS) in TAK patients.
  • To identify associated clinical features like inflammatory back pain, skin-mucosa lesions, and inflammatory eye disease.

Main Methods:

  • A cohort of 238 patients diagnosed with Takayasu's arteritis was retrospectively reviewed.
  • 198 patients completed a questionnaire and outpatient clinic visit to assess for concomitant inflammatory disorders.
  • Standardized forms collected data on IBD, AS, BS, autoimmune diseases, and specific clinical manifestations.

Main Results:

  • Of 198 TAK patients, 37 (19%) had diagnosed inflammatory bowel disease (6%), ankylosing spondylitis (8%), or Behçet's syndrome (5%).
  • Additionally, 6.5% had autoimmune diseases and 4.5% had miscellaneous inflammatory diseases.
  • Inflammatory back pain (35%), recurrent oral ulcers (14%), and erythema nodosum (12%) were common features, with only 32% of patients being free of any concomitant condition or feature.

Conclusions:

  • Takayasu's arteritis frequently co-occurs with inflammatory bowel disease, ankylosing spondylitis, and less commonly with Behçet's syndrome in approximately 19% of patients.
  • No clear temporal relationship was observed between the onset of TAK and these associated inflammatory conditions.
  • The high prevalence of inflammatory back pain in TAK patients warrants further investigation.