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Published on: April 3, 2016
Axial length as a basic anatomical predictor for morphological and clinical characteristics in acute central serous
Dmitrii S Maltsev1, Alexei N Kulikov2, Maria A Burnasheva2
1Department of Ophthalmology, Military Medical Academy, 5 Klinicheskaya St., St. Petersburg, 194044, Russia. glaz.med@yandex.ru.
Objectives:
To study the association between axial length (AL) and morphological and clinical characteristics in acute central serous chorioretinopathy.
Methods:
All patients received optical coherence tomography, fluorescein angiography (FA), optical biometry, and retro-mode scanning laser ophthalmoscopy. The distance between the leakage point and the centre of the fovea were defined using FA images, and its correlation with AL, subfoveal choroidal thickness (SCT), central retinal thickness (CRT), and neurosensory detachment (NSD) area was calculated. The number of leaks, rate of bilateral involvement, and recurrence rate was evaluated.
Results:
Forty-seven patients (47 eyes) were included in this study (38 males, 9 females, mean age 43.5 ± 10.8 years). The distance between the leakage point and the centre of the fovea had a correlation with AL (r = -0.38, p = 0.008), SCT (r = 0.51, p = 0.0004), and the area of NSD (r = 0.5, p = 0.0006) but not with CRT (r = -0.11, p = 0.45). A statistically significant difference in the distance between the leakage point and the centre of the fovea was found between eyes with short (<23.0 mm), medium (23.0-24.0 mm), and long (>24.0 mm) AL (p = 0.014). Number of leaks, rate of bilateral involvement, and recurrence rate had a negative linear association with AL (p < 0.05).
Conclusions:
AL appears to be the basic anatomical predictor, which associated with morphological and clinical characteristics in acute central serous chorioretinopathy.
