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Mesenteric Panniculitis with Raised Alanine Transaminase Levels: A Rare Case Report from Pakistan

Samar Mahmood1, Asim Sharif2, Khushboo Nusrat1

  • 1Internal Medicine, Dow University of Health Sciences, Karachi, PAK.

Cureus
|January 24, 2020
PubMed

Insights

Mesenteric panniculitis (MP) is a rare inflammatory condition affecting abdominal fat. This case highlights typical CT and histopathology findings in a patient presenting with abdominal pain and vomiting.

Area of Science:

  • Gastroenterology
  • Radiology
  • Pathology

Background:

  • Mesenteric panniculitis (MP) is a rare idiopathic condition involving inflammation and fibrosis of mesenteric adipose tissue.
  • Its etiology is unknown, with potential associations with other disorders.
  • Clinical presentation varies, often asymptomatic, but can include abdominal pain, weight loss, and ascites.

Observation:

  • A 45-year-old male presented with abdominal pain and vomiting.
  • Computed tomography (CT) revealed characteristic findings of MP, including mesenteric thickening, stranding, and a 'halo sign'.
  • Histopathology confirmed the diagnosis, and elevated alanine transaminase (ALT) levels were noted.

Findings:

  • CT imaging is crucial for diagnosing MP, showing specific patterns of mesenteric fat involvement.
  • Histopathology provides definitive diagnosis.
  • The case demonstrates a typical presentation of MP with associated elevated ALT levels.

Implications:

  • This case underscores the importance of recognizing characteristic CT findings for early MP diagnosis.
  • Understanding MP's varied presentations aids in clinical management.
  • Further research into MP etiology and associations is warranted.
Keywords:
alanine aminotransferasealanine transaminasegastroenterologyhalo signmesenteric panniculitismesenteric strandingmesenteric thickeningpakistan

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