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Updated: Dec 30, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Psoriasis and Treatment: Past, Present and Future Aspects
Claire Reid1, Christopher E M Griffiths
1Dermatology Centre, Salford Royal Hospital, University of Manchester, NIHR Manchester Biomedical Research Centre, M68HD Manchester, United Kingdom. claire.reid@manchester.ac.uk.
Psoriasis management has advanced with a better understanding of its causes. A holistic, patient-centered approach, including targeted therapies and comorbidity screening, improves outcomes for this complex skin disease.
Area of Science:
- Immunodermatology
- Translational Research
- Biopsychosocial Medicine
Background:
- Psoriasis pathogenesis understanding has evolved significantly over the last century.
- This evolution has driven substantial advancements in disease management strategies.
- Psoriasis is a common, complex skin condition with multifaceted origins.
Observation:
- Modern psoriasis treatment involves precise targeting of immune pathways using biologics and small molecules.
- Effective patient management requires a holistic approach, addressing the biopsychosocial aspects of the disease.
- A stratified medicine strategy is crucial for tailoring treatments to individual patient needs.
Findings:
- The integration of targeted therapies with a comprehensive, patient-centered care model optimizes psoriasis management.
- Early intervention and regular patient reviews are essential components of effective long-term care.
- Screening for comorbidities and providing patient education are vital for holistic management.
Implications:
- While a cure for psoriasis remains elusive, a systems-based approach enhances patient outcomes.
- Translational research has been pivotal in transforming psoriasis treatment paradigms.
- Future management will likely focus on personalized medicine and integrated care models for chronic inflammatory diseases.
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