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Enzyme abnormalities of patients with acquired immunodeficiency syndrome
C M Huang1, M Ruddel, R J Elin
1Clinical Pathology Department, Warren Grant Magnuson Clinical Center, Bethesda, MD 20892.
Abstract:
We determined the enzyme activities of glucose-6-phosphate isomerase, alanine aminotransferase, aspartate aminotransferase, and lactate dehydrogenase in serum from 23 normal controls, 27 anti-HIV seropositive individuals confirmed by Western blot, and 53 patients with acquired immunodeficiency syndrome (AIDS). There is a significant difference for all four enzyme activities among controls, HIV seropositive individuals, and patients with AIDS, the enzyme activities showing a progressive increase as the disease progresses. Evidently these enzyme measurements may be adjunctive biochemical markers for progression of AIDS.