Related Experiment Video
Updated: Dec 30, 2025

In Ovo Xenografting of Patient-Derived Acute Lymphoblastic Leukemia (ALL) Cells (PDX-ALL)
Published on: August 1, 2025
Lexicon for guidance terminology in pediatric hematology/oncology: A White Paper
L Lee Dupuis1, Paula D Robinson2, Marianne D van de Wetering3
1Research Institute and Department of Pharmacy, The Hospital for Sick Children, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.
Abstract:
Terms used to label types of clinical recommendations and guidance are applied inconsistently and do not reflect the methods used to create each type. Here, the international Pediatric Oncology Supportive Care Guideline Network proposes a lexicon for types of recommendations and guidance documents. A lexicon describing three types of recommendations (clinical practice guideline-derived, good practice statement, and expert opinion statement) and two types of guidance documents (clinical practice guideline and expert opinion) is presented. Consistent use of this lexicon will allow pediatric oncology clinicians to readily appreciate the methods used to create clinical guidance.
Related Concept Videos
Genetic Lingo
Lineage Commitment
Regulation of Hematopoietic Stem Cells
Standards of Care II
Pharmacokinetics in Pediatric Patients: Drug Excretion
Standards of Care I

