Related Experiment Video
Updated: Dec 30, 2025

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
Nodular Fat-Sparing Hepatic Parenchyma as 11C-Choline-Avid Finding on PET/CT
Ba Duong Nguyen1, Matthew T Heller, Michael C Roarke
1From Mayo Clinic, Scottsdale, AZ.
Focal nodular fat sparing in the liver can show high tracer uptake on PET/CT scans, mimicking tumors. This case highlights nodular hepatic fat sparing with C-choline avidity during prostate cancer recurrence assessment.
Area of Science:
- Radiology
- Nuclear Medicine
- Oncology
Background:
- Focal nodular fat sparing in the liver can present with increased tracer uptake on PET/CT.
- This finding, particularly with F-FDG, can be mistaken for liver neoplasms.
Observation:
- A case of nodular hepatic fat sparing was observed during PET/CT.
- The assessment was for biochemical recurrence of prostate cancer.
Findings:
- The focal nodular fat sparing demonstrated significant C-choline avidity.
- This finding occurred against a background of hepatic steatosis.
Implications:
- Nodular hepatic fat sparing exhibiting C-choline avidity can mimic malignancy on PET/CT.
- Awareness of this imaging pattern is crucial for accurate diagnosis in patients undergoing prostate cancer surveillance.
More Related Videos
07:47Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
Published on: August 31, 2022
09:49Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
Published on: December 2, 2013