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Related Experiment Video

Updated: Dec 30, 2025

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

Advances in Paper-Based Analytical Devices.

Tugba Ozer^1,2, Catherine McMahon¹, Charles S Henry¹

¹Department of Chemistry, Colorado State University, Fort Collins, Colorado 80526, USA;

Annual Review of Analytical Chemistry (Palo Alto, Calif.)

|January 28, 2020

Summary

This summary is machine-generated.

Microfluidic paper-based analytical devices (μPADs) offer versatile, low-cost analytical techniques for environmental and medical applications. Recent advancements in fabrication and detection modes enhance their performance and expand their use in field and lab studies.

Keywords:

biomedical diagnostics biosensors environmental microfluidics paper-based

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Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

Area of Science:

Analytical Chemistry
Materials Science
Biomedical Engineering

Background:

Microfluidic paper-based analytical devices (μPADs) represent an evolution of lab-on-a-chip technology.
μPADs are increasingly utilized for environmental analysis, complementing their established role in medical point-of-care diagnostics.

Purpose of the Study:

To review recent advancements in the fabrication, design, and detection methods of μPADs.
To highlight the expanding applications of μPADs in various analytical fields.

Main Methods:

Review of recent scientific literature on μPAD fabrication techniques beyond wax printing.
Analysis of diverse detection modes employed in μPADs.
Survey of reported applications in environmental and medical diagnostics.

Main Results:

Various fabrication methods exist, addressing challenges like solvent compatibility and device functionality.
Diverse detection strategies have been developed to enhance μPAD performance.
μPADs demonstrate significant potential for rapid, cost-effective measurements in both field and laboratory settings.

Conclusions:

μPADs are a rapidly developing technology with broad applicability.
Continued innovation in fabrication and detection will further enhance the utility of μPADs for critical measurement needs.