Adult Ileocolic Intussusception Caused by Diffuse Large B Cell Lymphoma
Joon Woo Park1, Geun Am Song1, Dong Hoon Baek1
1Department of Internal Medicine, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi
|January 28, 2020
Summary
Adult intussusception is rare, often caused by tumors. This case highlights small bowel diffuse large B-cell lymphoma as a cause, successfully treated with surgery and chemotherapy.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Adult intussusception is uncommon, comprising about 5% of all cases.
- Malignant tumors are identified as the leading cause in 80-90% of adult intussusceptions.
- The gastrointestinal tract is a frequent extranodal site for non-Hodgkin lymphoma.
Observation:
- A 69-year-old woman with no prior medical history presented with ileocolic intussusception.
- The intussusception was caused by a primary small bowel diffuse large B-cell lymphoma.
- This is a rare presentation of gastrointestinal lymphoma.
Findings:
- The patient underwent successful surgical resection of the affected small bowel segment.
- Adjuvant chemotherapy, including rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone, was administered.
- The patient achieved complete remission following treatment.
Implications:
- This case underscores the importance of considering lymphoma in the differential diagnosis of adult intussusception.
- Early diagnosis and multimodal treatment, including surgery and chemotherapy, are crucial for favorable outcomes.
- Further research into the optimal management of gastrointestinal lymphomas presenting as intussusception is warranted.
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