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Updated: Dec 30, 2025

Author Spotlight: MAPP Protocol – Advancing Glycan Analysis
Published on: September 29, 2023
Facile Structural Elucidation of Glycans Using NMR Spectroscopy Data and the Program CASPER: Application to the
Carolina Fontana1, Andrej Weintraub2, Göran Widmalm1
1Department of Organic Chemistry, Stockholm University, Arrhenius Laboratory, 106 91 Stockholm (Sweden), Fax: (+46) 815-49-08.
Abstract:
Time saver: The program CASPER was successfully employed to rapidly elucidate a new O-antigen polysaccharide structure (obtained from a strain of Escherichia coli serogroup O155), using solely unassigned NMR spectroscopy data as input information. Thus, what is considered the most tedious and time-consuming part of the structural elucidation process has been reduced from several hours (or even days) of manual interpretation to about four minutes of automated analysis.

