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Published on: May 22, 2014
Craniorachischisis with Exencephaly
Jessenia Guerrero1, Debra S Heller2, Ada Baisre de Leon2
1Pathology & Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Background:
Neural tube defects can be as mild as spina bifida, to as severe as anencephaly, with only a fraction of these cases presenting as both craniorachischisis and exencephaly. Case report: The G3, P1011 mother was 25-years old, who at an estimated fetal gestational age of 17 weeks had a fetal diagnosis of anencephaly based on a sonogram, resulting in elective pregnancy termination. The female fetus had an open neural tube defect, consisting of craniorachischisis and exencephaly. No abnormalities were noted in any other organs. Conclusion: Although mostly associated with anencephaly, craniorachischisis can also be associated with exencephaly in early pregnancy.
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