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Related Concept Videos

Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

312
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
312
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

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Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
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Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

330
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
330
Measurements of Strain01:27

Measurements of Strain

2.5K
Strain quantifies the deformation of a material under force, typically measured as normal strain, which represents the change in length when compared with the original length. Electrical strain gauges are used for enhanced accuracy. These devices consist of a conductive wire mounted on a paper backing that adheres to the material's surface. These gauges operate on the piezoresistive effect, where the wire's electrical resistance changes in response to mechanical deformation. The strain...
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Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

371
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
371

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Related Experiment Video

Updated: Dec 30, 2025

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
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Global longitudinal strain correlates to systemic right ventricular function.

Daniel Samarai1,2, Sandra Lindstedt Ingemansson3, Ronny Gustafsson3

  • 1Department of Clinical Sciences, Skåne University Hospital, Lund University, SE-221 85, Lund, Sweden. samaraidaniel@gmail.com.

Cardiovascular Ultrasound
|January 29, 2020
PubMed
Summary

Right ventricular global longitudinal strain, measured by cardiac magnetic resonance imaging (CMR), correlates with systemic right ventricular function in patients with congenital heart defects. This metric aids in evaluating ventricular function in these complex cases.

Keywords:
Atrial switchEchocardiographyGlobal longitudinal strainSystemic right ventricle

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Last Updated: Dec 30, 2025

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
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Area of Science:

  • Cardiology
  • Medical Imaging
  • Congenital Heart Disease

Background:

  • Systemic right ventricle (SRV) presents unique challenges in congenital heart disease management.
  • Evaluating SRV function is crucial for patient outcomes.
  • Existing methods may not fully capture SRV performance.

Purpose of the Study:

  • To assess the relationship between SRV function and various clinical parameters.
  • To investigate the utility of cardiac magnetic resonance imaging (CMR) in evaluating SRV function.
  • To explore correlations with echocardiography, exercise stress tests, NT-proBNP, and NYHA class.

Main Methods:

  • Retrospective study of patients with congenitally corrected transposition of the great arteries (ccTGA) or transposition of the great arteries (TGA) post-Mustard/Senning procedures.
  • Inclusion criteria: patients who underwent CMR, echocardiography, exercise stress test, and blood sampling.
  • Analysis focused on CMR-derived right ventricular ejection fraction and global longitudinal strain.

Main Results:

  • Eleven patients (median age 32 years) were analyzed.
  • A significant inverse correlation was found between CMR-derived right ventricular ejection fraction and right ventricular global longitudinal strain (r=-0.627, p=0.039).
  • This suggests RV global longitudinal strain reflects SRV systolic function.

Conclusions:

  • Right ventricular global longitudinal strain, assessed via CMR, is a valuable parameter for evaluating systemic right ventricular function.
  • This metric may improve the assessment of SRV in patients with ccTGA or TGA.
  • Further research can explore its prognostic implications.