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AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
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The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
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Related Experiment Video

Updated: Dec 29, 2025

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
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Postmortem urinary tract changes in cats with urethral obstruction.

Katie D Mauro1, Charles W Bradley1, Kenneth J Drobatz1

  • 1University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA.

Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001)
|January 29, 2020
PubMed
Summary
This summary is machine-generated.

Postmortem examinations revealed significant inflammatory lesions in the urinary bladders and kidneys of cats experiencing urethral obstruction (UO). The severity of these urinary tract findings correlated with elevated blood potassium levels in affected cats.

Keywords:
FICFLUTDUOobstructionpostmortem

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Area of Science:

  • Veterinary Pathology
  • Canine and Feline Medicine

Background:

  • Urethral obstruction (UO) is a critical condition in cats.
  • Understanding the postmortem urinary tract pathology is crucial for assessing disease severity.

Purpose of the Study:

  • To document gross and histopathological findings of the urinary tract in cats with UO.
  • To correlate these findings with the clinical severity of the disease.

Main Methods:

  • Retrospective, observational, descriptive study.
  • Analysis of complete postmortem examinations from 14 cats with UO.
  • Histopathological evaluation of urinary tract tissues.

Main Results:

  • Significant inflammatory lesions (cystitis, renal inflammation) were prevalent in cats with UO.
  • Lymphoplasmacytic infiltrates were common in renal lesions.
  • Hyperkalemia severity was associated with bladder and renal lesion severity.

Conclusions:

  • Cats with UO exhibit substantial inflammatory changes in the urinary bladder and kidneys.
  • The extent of these inflammatory lesions correlates with blood potassium levels.