Morbihan Syndrome, a UK Case Series

Area of Science:

• Dermatology
• Ophthalmology
• Plastic Surgery

Background:

• Morbihan syndrome is a rare condition.
• Characterized by slow-onset erythema and solid edema of the upper face.
• Often presents with features suggestive of complicated rosacea and chronic lymphedema.

Purpose of the Study:

• To describe the clinical characteristics of 10 patients with Morbihan syndrome.
• To review the existing literature on this rare condition.
• To evaluate treatment outcomes for Morbihan syndrome.

Main Methods:

• Retrospective case series of 10 patients.
• Review of relevant medical literature.
• Diagnosis supported by lid biopsy.

Main Results:

• The majority of patients were male (80%) with a mean age of 67 years.
• 60% presented with asymmetrical disease, predominantly on the right side.
• Histological findings indicated inflammation and vascular dysfunction, consistent with rosacea and lymphedema.
• Oral isotretinoin, intralesional triamcinolone, and debulking surgery showed variable success.

Conclusions:

• Morbihan syndrome is a rare, chronic condition.
• Treatment can be challenging, often requiring a multimodal approach.
• Interventions like isotretinoin, steroid injections, and surgery offer potential management options.