Dendrimers: Amazing Platforms for Bioactive Molecule Delivery Systems.

Area of Science:

• Nanotechnology and Materials Science
• Pharmaceutical Sciences
• Biomedical Engineering

Background:

• Dendrimers are key nanoparticles in modern drug delivery systems due to their unique physicochemical properties and structural modifiability.
• Their application as platforms for transporting bioactive molecules is driven by their ability to improve drug solubility, target tissue arrival, bioavailability, and controlled release.

Purpose of the Study:

• To review the latest therapeutic strategies employing dendrimers conjugated with bioactive molecules.
• To focus on advancements in drug delivery systems utilizing dendrimers for targeted therapies.

Main Methods:

• Literature review of recent studies on dendrimer-based drug delivery.
• Analysis of therapeutic applications in oncology and cardiology.
• Exploration of future research directions.

Main Results:

• Dendrimer nanoformulations significantly enhance the delivery of poorly soluble drugs.
• Conjugation of bioactive molecules to dendrimers improves therapeutic efficacy and controlled release.
• Recent studies highlight successful applications in cancer and cardiovascular disease treatments.

Conclusions:

• Dendrimers represent a promising platform for advanced drug delivery systems.
• Further research into dendrimer conjugation holds potential for novel therapeutic strategies.
• The review underscores the expanding role of dendrimers in treating complex diseases.