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Microsporidial stromal keratitis in a cat
Kelly A Caruso1, Seth Koch2, Benjamin D Reynolds1
1Eye Clinic for Animals, 57-63 Herbert St, Artarmon, Sydney, 2064, Australia.
Medical Mycology Case Reports
|January 30, 2020
Summary
A feline patient experienced eye pain due to microsporidial stromal keratitis, a rare condition. Diagnosis involved histopathology and electron microscopy confirming Microspora infection.
Area of Science:
- Veterinary Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Ocular pain and corneal opacity are common presenting signs in felines.
- Fungal and protozoal infections can cause stromal keratitis, impacting vision.
- Microsporidial infections are increasingly recognized in veterinary medicine.
Observation:
- A 12-year-old female cat presented with a 35-day history of right eye pain.
- Ophthalmic examination revealed a sub-epithelial corneal opacity.
Findings:
- Histopathology identified Gram, Hematoxylin-eosin, and Gomori methanamine-silver positive spores.
- Transmission electron microscopy confirmed ultrastructural findings consistent with Microspora.
- This represents the second reported case of microsporidial stromal keratitis in a felid.
Implications:
- This case expands the understanding of Microspora as a cause of feline keratitis.
- Early diagnosis and treatment of microsporidial keratitis are crucial for visual outcomes in cats.
- Further research into feline microsporidial infections is warranted.

