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Developing the Evidence-Grading Tools and Process for the Complex Attention-Deficit/Hyperactivity Disorder Guideline.

Eugenia Chan1, Tanya E Froehlich2, William J Barbaresi1

  • 1Division of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.

Journal of Developmental and Behavioral Pediatrics : JDBP
|January 31, 2020
PubMed
Summary
This summary is machine-generated.

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This study details a novel evidence grading approach for complex Attention-Deficit Hyperactivity Disorder (ADHD) clinical practice guidelines (CPGs), addressing resource limits and diverse reviewer readiness.

Area of Science:

  • Pediatrics
  • Clinical Practice Guidelines
  • Evidence-Based Medicine

Background:

  • Clinical practice guidelines (CPGs) require rigorous evidence assessment.
  • The Society for Developmental and Behavioral Pediatrics (SDBP) faced challenges in grading evidence for complex Attention-Deficit Hyperactivity Disorder (ADHD).
  • Resource constraints necessitated an innovative evidence grading strategy.

Purpose of the Study:

  • To describe challenges in evidence grading for the SDBP Complex ADHD CPG.
  • To discuss the rationale, process, and tools for their evidence grading approach.
  • To report on reviewer experiences and readiness for evidence grading.

Main Methods:

  • Development of a novel, rigorous evidence grading approach.
  • Utilizing diverse volunteer reviewers with research methodology backgrounds.

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  • Systematic evaluation of evidence quality for guideline recommendations.

    • Main Results:

    • Challenges in evidence grading for complex ADHD were identified.
    • A detailed rationale, process, and specific tools for evidence grading were established.
    • Reviewer experiences and readiness were assessed, highlighting preparedness for the task.

    Conclusions:

    • The SDBP developed an innovative evidence grading method for complex ADHD CPGs.
    • This approach addressed evidence quality assessment under resource constraints.
    • The methodology can serve as a model for other CPG development groups.