The relationship between body mass index and renal length in obese children

Gönül Parmaksız1, Şenay Demir Kekeç2, Nurcan Dinler Cengiz3

  • 1Faculty of Medicine Seyhan, Adana Dr. Turgut Noyan Training and Research Center, Department of Pediatric Nephrology, Başkent University, Adana, Turkey. gonulped1@hotmail.com.

Insights

Pediatric obesity is a growing concern. This study found a significant relationship between body mass index (BMI) and kidney size in children, developing nomograms to aid in evaluating renal length in obese youth.

Area of Science:

  • Pediatric Nephrology
  • Medical Imaging
  • Public Health

Background:

  • Pediatric obesity is a significant public health issue linked to numerous comorbidities.
  • Renal length is a crucial parameter for diagnosing and monitoring kidney diseases.
  • Understanding renal size in relation to body mass is vital for pediatric health assessments.

Purpose of the Study:

  • To investigate the correlation between ultrasonographically measured renal length and body mass index (BMI) in obese children.
  • To establish nomograms for renal length based on BMI in the pediatric population.
  • To provide a tool for better evaluation of renal size in overweight and obese children.

Main Methods:

  • Renal ultrasound performed on 368 children without renal disease.
  • Children categorized into normal weight, overweight, and obese groups based on BMI percentiles.
  • Analysis of age, gender, weight, height, and renal length (right and left) in relation to BMI.

Main Results:

  • Significant differences in weight, height, BMI, and renal length were observed across the BMI groups (p=0.001).
  • Renal length showed significant correlations with BMI, age, and height.
  • Developed nomograms for renal length in obese children using multiple regression analysis (R²=0.32, p=0.0001).

Conclusions:

  • Ultrasonographic renal length measurement correlated with BMI in children.
  • Nomograms can assist in evaluating renal size, particularly in obese children where smaller kidneys might be missed.
  • This method provides an additional tool for assessing renal dimensions in pediatric obesity.
Abstract

Related Concept Videos

Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
167
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.1K
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration01:28

Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area.
125
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
190
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
128
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
3.1K