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Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic

Raffaele Coppini1, Cecilia Ferrantini2,3, Josè Manuel Pioner2

  • 1Department NeuroFarBa, University of Florence, Florence, Italy.

JACC. Basic to Translational Science
|January 31, 2020
PubMed

Keywords:
AP, action potentialDAD, delayed afterdepolarizationEAD, early afterdepolarizationECG, electrocardiographyHCM, hypertrophic cardiomyopathyICa-L, L-type Ca currentIK, delayed-rectifier K currentINaL, late Na currentLVOT, left ventricular outflow tractNCX, Na+/Ca2+ exchangerQT intervalRyR, ryanodine receptorSR, sarcoplasmic reticulumaction potentialsarrhythmiasdiastolic dysfunctionhERG, human ether-à-go-go-related genehypertrophic cardiomyopathypCa, Ca activation levelsafety

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