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Updated: Dec 29, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Community pharmacists as catalysts for deprescribing: An exploratory study using quality improvement processes
Barbara Farrell1,2,3,4,5,6,7,8, Chantalle Clarkin1,2,3,4,5,6,7,8, James Conklin1,2,3,4,5,6,7,8
1Bruyère Research Institute (Farrell, Clarkin, Conklin, Irving), University of Ottawa, Ottawa.
Community pharmacists can integrate deprescribing into daily practice. Training and workflow strategies enhance their capacity to reduce medications that may cause more harm than benefit, especially in elderly patients.
Area of Science:
- Pharmacology
- Geriatrics
- Health Services Research
Background:
- Growing international focus on deprescribing, the reduction or cessation of medications.
- Elderly individuals are a key population benefiting from deprescribing due to potential harm outweighing benefits.
- Community pharmacists are strategically positioned to facilitate deprescribing initiatives.
Purpose of the Study:
- To enhance community pharmacists' ability to incorporate deprescribing into their routine practice.
- To develop effective training and workflow strategies for pharmacist-led deprescribing.
- To explore the feasibility and implementation of deprescribing services in community pharmacy settings.
Main Methods:
- Exploratory mixed-methods design, primarily qualitative.
- Training provided to pharmacy staff on deprescribing guidelines.
- Data collection through observations, advisory meetings, and Plan-Do-Study-Act (PDSA) cycles.
- Quantitative process and output measures analyzed.
Main Results:
- All participating pharmacies established deprescribing goals, though specific approaches varied.
- Deprescribing activities were successfully integrated into daily workflows.
- Key themes included staff capacity building, patient interaction strategies, medication reviews, and follow-up processes.
- Pharmacy approaches evolved over time through iterative PDSA cycles.
Conclusions:
- Deprescribing is a feasible service within community pharmacy settings.
- The study informed the development of a business model for implementing deprescribing services.
- Further development of business models is recommended to support widespread deprescribing adoption.
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