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Updated: Dec 29, 2025

Real-Time Void Spot Assay
Published on: February 10, 2023
Variable urine Histoplasma antigen with volume status
Allyson Hughes1, Joy Underwood1, George E Nelson2
1The Department of Medicine, University of Tennessee Health Science Center, Saint Thomas-UT Internal Medicine Clinic, Nashville, TN, USA.
Abstract:
A patient with progressive disseminated histoplasmosis was noted to have an increase in urine Histoplasma antigen level during monitoring of her disease. The patient revealed she had inadequately hydrated, and her urine volume was low and subjectively concentrated. Following hydration, urine antigen was retested and became undetectable.
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