Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

231
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
231
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

315
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
315

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thermal Ablation with or without Liver Transplantation for Hepatocellular Carcinoma in Older Adults with Child-Pugh Class A Cirrhosis.

Journal of vascular and interventional radiology : JVIR·2026
Same author

Selecting Pharmacologic Interventions for MASH.

Digestive diseases and sciences·2026
Same author

Combination Immunotherapy and Yttrium-90 Radioembolization in Hepatocellular Carcinoma: Biological Rationale, Clinical Evidence, and Future Directions.

Cancers·2026
Same author

Refractory Ascites and the Alfapump.

Gastro hep advances·2026
Same author

Gastroenterologist's Guide to Assess for Alcohol Use.

Digestive diseases and sciences·2026
Same author

Toward the simultaneous detection of multiple diseases with a highly cost-effective cell-free DNA methylome test.

Proceedings of the National Academy of Sciences of the United States of America·2026

Related Experiment Video

Updated: Dec 29, 2025

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
08:45

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation

Published on: June 27, 2025

1.3K

Retrograde Transvenous Obliteration (RTO): A New Treatment Option for Hepatic Encephalopathy.

Edward Wolfgang Lee1,2, Audrey E Lee3, Sammy Saab4,5

  • 1Division of Interventional Radiology, Department of Radiology, UCLA Medical Center, Ronald Reagan Medical Center at UCLA, David Geffen School of Medicine at UCLA, 757 Westwood Plaza, Los Angeles, CA, 90095-743730, USA. EdwardLee@mednet.ucla.edu.

Digestive Diseases and Sciences
|February 1, 2020
PubMed
Summary
This summary is machine-generated.

Retrograde transvenous obliteration (RTO) shows promise in treating hepatic encephalopathy (HE) by closing liver shunts. While more research is needed, RTO may offer an alternative for patients unresponsive to traditional HE therapies.

Keywords:
BRTOCARTOCirrhosisHepatic encephalopathyPARTORTO

More Related Videos

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
04:41

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

1.5K
Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
05:31

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients

Published on: September 20, 2020

6.0K

Related Experiment Videos

Last Updated: Dec 29, 2025

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
08:45

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation

Published on: June 27, 2025

1.3K
Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
04:41

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

1.5K
Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
05:31

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients

Published on: September 20, 2020

6.0K

Area of Science:

  • Hepatology
  • Interventional Radiology
  • Neurology

Background:

  • Hepatic Encephalopathy (HE) is a severe complication of liver disease, characterized by brain dysfunction due to portosystemic shunting.
  • Current treatments for HE focus on managing hyperammonemia, antibiotics, and probiotics, with varying success rates.

Purpose of the Study:

  • To explore the potential of retrograde transvenous obliteration (RTO) as a treatment for hepatic encephalopathy (HE).
  • To evaluate RTO's efficacy in managing HE when conventional therapies fail.

Main Methods:

  • Review of RTO procedures, an established method for managing gastric varices, applied to occlude spontaneous portosystemic shunts.
  • Analysis of preliminary outcomes in HE patients undergoing RTO.

Main Results:

  • RTO demonstrated promising results in reducing the severity of hepatic encephalopathy.
  • Potential side effects include transient worsening of portal hypertension and new shunt formation.

Conclusions:

  • RTO presents a potentially effective alternative treatment for refractory hepatic encephalopathy.
  • Further studies are required to confirm long-term efficacy and safety of RTO for HE management.