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Updated: Aug 13, 2026

Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity
Published on: January 10, 2013
[Impulse activity of slowly adapting pulmonary receptors during respiration]
Abstract:
Impulse activity of 50 pulmonary slow-adapting receptors (SAR) has been investigated in anesthetized cats during eupnea under conditions of quasi-static and dynamic lung inflation. During inspiration 74% SARs were found to have nonlinear relationship between the receptor frequency (F) and pulmonary volume (V), in 16% receptors the F-V relationship was linear. Impulse activity of 10% SARs had different characteristics. During quasi-static inflation 40% SARs had the nonlinear F-V relationship, 50% SARs had the linear one. During dynamic inflation 70% SARs had the nonlinear F-V relationship, 20% SARs had the linear one. The F-V relationship of the afferent output from all investigated SARs was nonlinear during eupnea. Differences in the F-V relationships of SARs during lung inflation and eupnea as well as possible synaptic connections of SARs with bulbar respiratory neurons are discussed.
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