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Visualization and Analysis of Protein Structures with LiteMol Suite
David Sehnal1,2, Radka Svobodová3,4, Karel Berka5
1CEITEC-Central European Institute of Technology, Masaryk University Brno, Brno-Bohunice, Czech Republic.
Methods in Molecular Biology (Clifton, N.J.)
|February 2, 2020
Summary
LiteMol provides fast delivery of biomacromolecular structural data for interactive visualization. This suite integrates data services, compression, and a viewer for web and mobile use.
Area of Science:
- Structural Biology
- Bioinformatics
- Computational Chemistry
Background:
- Accessing and visualizing biomacromolecular structural data is crucial for understanding biological processes.
- Existing methods for data delivery and visualization can be slow and lack interactivity across devices.
Purpose of the Study:
- To introduce the LiteMol suite as an innovative solution for near-instant delivery and interactive visualization of structural data.
- To describe the components and functionalities of the LiteMol suite for visual inspection of protein structures.
Main Methods:
- The LiteMol suite combines data delivery services (CoordinateServer, DensityServer) with a BinaryCIF compression format.
- It incorporates the LiteMol Viewer for interactive visualization across modern web browsers and mobile devices.
- Integration into major life science databases like the Protein Data Bank in Europe (PDBe).
Main Results:
- Achieves near-instant delivery of biomacromolecular structural data.
- Provides an interactive and responsive user experience on various devices.
- Offers advanced functionalities including annotations and powerful selection features for detailed structural analysis.
Conclusions:
- The LiteMol suite offers an efficient and accessible platform for exploring biomacromolecular structures.
- Its integration and advanced features enhance the visual inspection of protein structures for researchers.
- The open-source availability promotes wider adoption and development within the life sciences community.
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