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Published on: April 26, 2024
Association between residual symptoms and social functioning in patients with depression
Yun Wang1, Gang Wang2, Ning Zhang3
1Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Residual symptoms in Chinese depression patients significantly impair social functioning. Key factors include loss of interest, anxiety, appetite changes, low energy, sleep disorders, older age, and longer disease duration.
Area of Science:
- Psychiatry and Mental Health
- Clinical Psychology
- Epidemiology
Background:
- Limited data exists on residual symptoms in Chinese depression patients.
- Residual symptoms and their impact on social functioning require further investigation in this population.
Purpose of the Study:
- To evaluate the association between residual symptoms and social functional impairment in Chinese patients with depression.
Main Methods:
- A multicenter, cross-sectional study involving 1503 patients across 11 hospitals in China.
- Assessment of residual symptoms and social functioning using validated scales (SDS, QIDS-SR16, Q-LES-Q-SF, PHQ-15).
- Logistic regression analysis to identify factors associated with social functional impairment.
Main Results:
- 39.1% of patients experienced social functional impairment.
- Impaired patients exhibited higher physical symptoms (PHQ-15), more residual depressive symptoms (QIDS dimensions), and lower quality of life (Q-LES-Q-SF).
- Significant predictors of impairment included loss of interest, mental anxiety, appetite changes, low energy, sleep disorders, older age, and longer disease duration.
Conclusions:
- Patients with impaired social function report more physical symptoms, residual depression, and lower quality of life.
- Residual symptoms are significantly associated with social functional impairment in depression.
- Findings highlight the importance of addressing residual symptoms to improve social functioning in depressed Chinese patients.
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